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KMID : 0363219920300020217
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Korean Journal of Dermatology
1992 Volume.30 No. 2 p.217 ~ p.220
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Noduloulcerative Syphilis
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이인준
최은선/김동건/이민걸/이정복
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Abstract
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A 26-year-old female presented heraelf to our clinic due to noduloucerative lesions of one month duration on her face and trunk with accompaning headache and mild fever. In family history, her husband was reported to have a history of chancre. On
physical examination. rice sized eythematous papules and bean sized nodules with central ulceration were seen on the face and trunk. VDRL was 1:31 positive. A skin biopsy of a noduloulcerative lesion showed ulceration, vascular dilatation with
fibrinoid
chages and perivascular inflammatory cellu infiltrations. especially plasma cells. Immunoperoxidase stain showed T. pallidum at the epidermis and papillary dermis. The diagnsis was made as secondary syphilis with unusual clinical presentation as
noduloucerative skin lesions. The skin lesions completely disappeared one month after treatment with injection of benzathine penicillin G 2.4 million unit intramuscularly weekly for three times. (Kor J Dermatol 1992; 30 (2) : 217-220)
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